Proteomics Core Facility

2024

Dobert JP, Bub S, Mächtel R, Januliene D, Steger L, Regensburger M, Wilfling S, Chen J,Dejung M, Plötz S, Hehr U, Moeller A, Arnold P and Zunke F (2024) Activation and purification of ß-glucocerebrosidase by exploiting its transporter LIMP-2 - implications for novel treatment strategies in Gaucher's and Parkinson's disease. Adv Sci (Weinh), 11:e2401641 Link  

Hutten S, Chen JX, Isaacs AM and Dormann D ( 2024 ) Poly-GR impairs PRMT1-mediated arginine methylation of disease-linked RNA-binding proteins by acting as a substrate sink. Biochemistry , doi: 10.1021/acs.biochem.4c00308 Link

Schmidt A, Allmann S, Schwarzenbach C, Snyder P, Chen J, Nagel G, Schöneis A, Rasenberger B, Beli P, Loewer A, Hofmann TG, Tomicic MT and Christmann M (2024) The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence. Nucleic Acids Res, 23:gkae426 Link

Schmidt A, Zhang H, Schmitt S, Rausch C, Popp O, Chen J, Cmarko D, Butter F, Dittmar G, Lermyte F and Cardoso MC (2024) The proteomic composition and organization of constitutive heterochromatin in mouse tissues. Cells, 13:139 Link

2023

Greither T^#, Dejung M, Behre HM, Butter F and Herlyn H^# (2023) The human sperm proteome — toward a panel for male fertility testing. Andrology, 11:1418–1436 (^#indicates joint correspondence) Link

Maus H, Gellert A, Englert OR, Chen JX, Schirmeister T and Barthels F (2023) Designing photoaffinity tool compounds for the investigation of the DENV NS2B-NS3 protease allosteric binding pocket. RSC Med Chem, 14:2365-2379 Link

Nischwitz E, Schoonenberg VAC, Fradera-Sola A, Dejung M, Vydzhak O, Levin M, Luke B, Butter F and Scheibe M (2023) DNA damage repair proteins across the Tree of Life. iScience, 26:106778 Link

Penner I, Dejung M, Freiwald A, Butter F, Chen JX and Plachter B (2023) Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies. Sci Data, 10:517 Link

Rahmanto AS, Blum CJ, Scalera C, Heidelberger JB, Mesitov M, Horn-Ghetko D, Gräf JF, Mikicic I, Hobrecht R, Orekhova A, Ostermaier M, Ebersberger S, Möckel MM, Krapoth N, Da Silva Fernandes N, Mizi A, Zhu Y, Chen JX, Choudhary C, Papantonis A, Ulrich HD, Schulman BA, König J and Beli P (2023) K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution. Mol Cell, 83:4272-4289.e10 Link

Renz C, Asimaki E, Meister C, Albanèse V, Petriukov K, Krapoth NC, Wegmann S, Wollscheid HP, Wong RP, Fulzele A, Chen JX, Léon S and Ulrich HD (2023) Ubiquiton-An inducible, linkage-specific polyubiquitylation tool. Mol Cell, 84:386-400.e11Link

2022

Hanisch D, Krumm A, Diehl T, Stork CM, Dejung M, Butter F, Kim E, Brenner W, Fritz G, Hofmann TG and Roos WP (2022) Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression. Cell Death Dis, 13:293 Link

Kong G, Zhou L, Freiwald A, Shkura K and Di Giovanni S (2022) Purification of mouse axoplasmic proteins from dorsal root ganglia nerves for proteomics analysis. STAR Protoc, 3:101166 Link

Krauter S, Büscher N, Bräuchle E, Ortega Iannazzo S, Penner I, Krämer N, Gogesch P, Thomas S, Kreutz M, Dejung M, Freiwald A, Butter F, Waibler Z and Plachter B (2022) An attenuated strain of human cytomegalovirus for the establishment of a subviral particle vaccine. Vaccines, 10:1326 Link

Kunert F, Metzner FJ, Jung J, Höpfler M, Woike S, Schall K, Kostrewa D, Moldt M, Chen JX, Bantele S, Pfander B, Eustermann S and Hopfner KP (2022) Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8:eadd3189 Link

Öztürk M, Freiwald A, Cartano J, Schmitt R, Dejung M, Luck K, Al-Sady B, Braun S, Levin M and Butter F (2022) Proteome effects of genome-wide single gene perturbations. Nat Commun, 13:6153 Link

Penner I, Büscher N, Dejung M, Freiwald A, Butter F and Plachter B (2022) Subviral dense bodies of human cytomegalovirus induce an antiviral type I Interferon response. Cells, 11:4028 Link

Prieto Huarcaya S, Drobny A, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P and Zunke F (2022) Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models. Autophagy, 18:1127-1151 Link

2021

Zhang X, Harding BW, Aggad D, Courtine D, Chen JX, Pujol N and Ewbank JJ (2021) Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. PLoS Genet, 17:e1009600 Link 

Zimmermann C, Krämer N, Krauter S, Strand D, Sehn E, Wolfrum U, Freiwald A, Butter F and Plachter B (2021) Autophagy interferes with human cytomegalovirus genome replication, morphogenesis, and progeny release. Autophagy, 17:779-795 Link  

2020

Doleželová E, Kunzová M, Dejung M, Levin M, Panicucci B, Regnault C, Janzen CJ, Barrett MP, Butter F and Zíková A (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLoS Biol, 18:e3000741 Link

Greither T, Schumacher J, Dejung M, Behre HM, Zischler H, Butter F and Herlyn H (2020) Fertility relevance probability analysis shortlists genetic markers for male fertility impairment. Cytogenet Genome Res, 160:506-522 Link

Kong G*, Zhou L*, Serger E, Palmisano I, De Virgiliis F, Hutson TH, Mclachlan E, Freiwald A, La Montanara P, Shkura K, Puttagunta R and Di Giovanni S (2020) AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury. Nat Metab, 2:918–933 (*indicates joint contribution) Link

2019

Bluhm A, Viceconte N, Li F, Rane G, Ritz S, Wang S, Levin M, Shi Y, Kappei D and Butter F (2019) ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2. Nucleic Acids Res, 47:1896–1907 Link

Cordeiro Rodrigues RJ, de Jesus Domingues AM, Hellmann S, Dietz S, de Albuquerque BFM, Renz C, Ulrich HD, Sarkies P, Butter F and Ketting RF (2019) PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability. Genes Dev, 33:857–870 Link

Goos C, Dejung M, Wehman AM, M-Natus E, Schmidt J, Sunter J, Engstler M, Butter F^# and Kramer S^# (2019) Trypanosomes can initiate nuclear export co-transcriptionally. Nucleic Acids Res, 47:266–282 (^#indicates joint correspondence) Link

Pons M, Nagel G, Zeyn Y, Beyer M, Laguna T, Brachetti T, Sellmer A, Mahboobi S, Conradi R, Butter F and Kramer OH (2019) Human platelet lysate as validated replacement for animal serum to assess chemosensitivity. ALTEX, 36:277–288 Link

Warncke JD, Passecker A, Kipfer E, Brand F, Pérez-Martínez L, Proellochs NI, Kooij TWA, Butter F, Voss TS^# and Beck HP^# (2019) The PHIST protein GEXP02 targets the host cytoskeleton during sexual development of Plasmodium falciparum. Cell Microbiol, 22:e13123 (^#indicates joint correspondence) Link 

Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei A-E, Chen C-W, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW and Ramming A (2019) PU.1 controls fibroblast polarization and tissue fibrosis. Nature, 566:344–349 Link

2018

Almeida MV, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, Ulrich HD, König J, Butter F and Ketting RF (2018) GTSF‐1 is required for formation of a functional RNA‐dependent RNA Polymerase complex in Caenorhabditis elegans. EMBO J, 37:e99325 Link

Baldi S, Jain DS, Harpprecht L, Zabel A, Scheibe M, Butter F, Straub T and Becker PB (2018) Genome-wide rules of nucleosome phasing in Drosophila. Mol Cell, 72:661–672.e4 Link

Becker K, Bluhm A*, Casas-Vila N*, Dinges N*, Dejung M, Sayols S, Kreutz C, Roignant JY, Butter F^# and Legewie S^# (2018) Quantifying post-transcriptional regulation in the development of Drosophila melanogaster. Nat Commun, 9:4970 (*indicates joint contribution, ^#indicates joint correspondence) Link

Charbonnel C, Rymarenko O, Da Ines O, Benyahya F, White CI, Butter F and Amiard S (2018) The linker histone GH1-HMGA1 is involved in telomere stability and DNA damage repair. Plant Physiol, 177:311–327 Link

Dal Magro C, Keller P, Kotter A, Werner S, Duarte V, Marchand V, Ignarski M, Freiwald A, Müller R-U, Dieterich C, Motorin Y, Butter F, Atta M and Helm M (2018) A vastly increased chemical variety of RNA modifications containing a thioacetal structure. Angew Chemie Int Ed, 57:7893–7897 Link

Harris CJ*, Scheibe M*, Wongpalee SP, Liu W, Cornett EM, Vaughan RM, Li X, Chen W, Xue Y, Zhong Z, Yen L, Barshop WD, Rayatpisheh S, Gallego-Bartolome J, Groth M, Wang Z, Wohlschlegel JA, Du J, Rothbart SB, Butter F^# and Jacobsen SE^# (2018) A DNA methylation reader complex that enhances gene transcription. Science, 362:1182–1186 (*indicates joint contribution, #indicates joint correspondence) Link

Kiweler N, Brill B, Wirth M, Breuksch I, Laguna T, Dietrich C, Strand S, Schneider G, Groner B, Butter F, Heinzel T, Brenner W and Krämer OH (2018) The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells. Arch Toxicol, 92:2227–2243 Link

Pons M, Reichardt CM, Hennig D, Nathan A, Kiweler N, Stocking C, Wichmann C, Christmann M, Butter F, Reichardt S, Schneider G, Heinzel T, Englert C, Hartkamp J, Krämer OH and Mahendrarajah N (2018) Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells. Arch Toxicol, 92:2119–2135 Link

Reis H, Schwebs M, Dietz S, Janzen CJ and Butter F (2018) TelAP1 links telomere complexes with developmental expression site silencing in African trypanosomes. Nucleic Acids Res, 46:2820–2833 Link

Roovers EF, Kaaij LJT, Redl S, Bronkhorst AW, Wiebrands K, de Jesus Domingues AM, Huang H-Y, Han C-T, Riemer S, Dosch R, Salvenmoser W, Grün D, Butter F, van Oudenaarden A and Ketting RF (2018) Tdrd6a regulates the aggregation of Buc into functional subcellular compartments that drive germ cell specification. Dev Cell, 46:285–301.e9 Link

Winzi M, Casas Vila N, Paszkowski-Rogacz M, Ding L, Noack S, Theis M, Butter F and Buchholz F (2018) The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells. PLOS One, 13:e0191682 Link

2017

Casas-Vila N*, Bluhm A*, Sayols S*, Dinges N, Dejung M, Altenhein T, Kappei D, Altenhein B, Roignant JY and Butter F (2017) The developmental proteome of Drosophila melanogaster. Genome Res, 27:1273–1285 (*indicates joint contribution) Link

Goos C, Dejung M, Janzen CJ, Butter F and Kramer S (2017) The nuclear proteome of Trypanosoma brucei. PLOS One, 12:e0181884 Link

Jahn A*, Rane G*, Paszkowski‐Rogacz M, Sayols S, Bluhm A, Han C, Draškovič I, Londoño‐Vallejo JA, Kumar AP, Buchholz F^#, Butter F^# and Kappei D^# (2017) ZBTB48 is both a vertebrate telomere‐binding protein and a transcriptional activator. EMBO Rep, 18:929–946 (*indicates joint contribution, ^#indicates joint correspondence) Link

Lebedeva S, de Jesus Domingues AM, Butter F and Ketting RF (2017) Characterization of genetic loss-of-function of Fus in zebrafish. RNA Biol, 14:29–35 Link

2016

Bluhm A, Casas-Vila N, Scheibe M and Butter F (2016) Reader interactome of epigenetic histone marks in birds. Proteomics, 16:427–436 Link

Cicova Z, Dejung M, Skalicky T, Eisenhuth N, Hanselmann S, Morriswood B, Figueiredo LM, Butter F^# and Janzen CJ^# (2016) Two flagellar BAR domain proteins in Trypanosoma brucei with stage-specific regulation. Sci Rep, 6:35826 (^#indicates joint correspondence) Link

Dejung M, Subota I, Bucerius F, Dindar G, Freiwald A, Engstler M, Boshart M, Butter F^# and Janzen CJ^# (2016) Quantitative proteomics uncovers novel factors involved in developmental differentiation of trypanosoma brucei. PLOS Pathog, 12:e1005439 (^#indicates joint correspondence) Link

Klassen R, Ciftci A, Funk J, Bruch A, Butter F and Schaffrath R (2016) tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast. Nucleic Acids Res, 44:10946–10959 Link

Wagner SA, Oehler H, Voigt A, Dalic D, Freiwald A, Serve H and Beli P (2016) ATR inhibition rewires cellular signaling networks induced by replication stress. Proteomics, 16:402–416 Link

2015

Casas-Vila N, Scheibe M, Freiwald A, Kappei D and Butter F (2015) Identification of TTAGGG-binding proteins in Neurospora crassa, a fungus with vertebrate-like telomere repeats. BMC Genomics, 16:965 Link

Roovers EF, Rosenkranz D, Mahdipour M, Han CT, He N, Chuva de Sousa Lopes SM, van der Westerlaken LAJ, Zischler H, Butter F, Roelen BAJ and Ketting RF (2015) Piwi proteins and piRNAs in mammalian oocytes and early embryos. Cell Rep, 10:2069–2082 Link

2014

Hornburg D, Drepper C, Butter F, Meissner F, Sendtner M and Mann M (2014) Deep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics. Mol Cell Proteomics, 13:3410–3420 Link

Machyna M, Kehr S, Straube K, Kappei D, Buchholz F, Butter F, Ule J, Hertel J, Stadler PF and Neugebauer KM (2014) The coilin interactome identifies hundreds of small noncoding RNAs that traffic through cajal bodies. Mol Cell, 56:389–399 Link

2024

Martínez-Lumbreras S, Träger LK, Mulorz MM, Payr M, Dikaya V, Hipp C, König J and Sattler M (2024) Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs. Nat Commun, 15:3888 Link

Medina-Suárez S, Ayra-Plasencia J, Pérez-Martínez L, Butter F and Machín F (2024) Msc1 is a nuclear envelope protein that reinforces DNA repair in late mitosis. iScience, 27:110250 Link

Sushkin ME, Jung M and Lemke EA ( 2024 ) Tuning the functionality of designer translating organelles with orthogonal tRNA synthetase/tRNA pairs. J Mol Biol , 30:168728 Link

2023

Bronkhorst AW, Lee CY, Möckel MM, Ruegenberg S, de Jesus Dominques AM, Sadouki S, Piccinno R, Sumiyoshi T, Siomi MC, Stelzl L, Luck K and Ketting RF (2023) An extended Tudor domain within Vreteno interconnects Gtsf1L and Ago3 for piRNA biogenesis in Bombyx mori. EMBO J, 42:e114072 Link

Fradera-Sola A, Nischwitz E, Bayer ME, Luck K and Butter F (2023) RNA-dependent interactome allows network-based assignment of RNA-binding protein function. Nucleic Acids Res, 51:5162–5176 Link

Kalita AI, Marois E*, Kozielska M, Weissing FJ, Jaouen E, Möckel MM, Rühle F, Butter F, Basilicata MF* and Keller Valsecchi CI* (2023) The sex-specific factor SOA controls dosage compensation in Anopheles mosquitos. Nature, 623:175–182 (*indicates joint contribution) Link

Koehler C, Sauter PF, Klasen B, Waldmann C, Pektor S, Bausbacher N, Lemke EA and Miederer M (2023) Genetic code expansion for site-specific labeling of antibodies with radioisotopes. ACS Chem Biol, 18:443–448 Link

Pires VB, Lohner N, Wagner T, Wagner CB, Wilkens M, Hajikazemi M, Paeschke K, Butter F and Luke B (2023) RNA-DNA hybrids prevent resection at dysfunctional telomeres. Cell Rep, 42:112077 Link

Shi J, Hauschulte K, Mikicic I, Maharjan S, Arz V, Strauch T, Heidelberger JB, Schaefer JV, Dreier B, Plückthun A, Beli P, Ulrich HD and Wollscheid HP (2023) Nuclear myosin VI maintains replication fork stability. Nat Commun, 14:3787 Link

Stier A, Gilberto S, Mohamed WI, Royall LN, Helenius J, Mikicic I, Sajic T, Beli P, Müller DJ, Jessberger S and Peter M (2023) The CUL4B-based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho-specific DCAFs. EMBO J, 42:e112847 Link

Sun R, Meng Z, Lee H, Offringa R and Niehrs C (2023) ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation. Cell Chem Biol, 30:739–752.e8 Link 

Sushkin ME*, Koehler C* and Lemke EA (2023) Remodeling the cellular stress response for enhanced genetic code expansion in mammalian cells. Nat Commun, 14:6931 (*indicates joint contribution) Link  

Vu HH*, Behrmann H*, Hanić M, Jeyasankar G, Krishnan S, Dannecker D, Hammer C, Gunkel M, Solov'yov IA, Wolf E and Behrmann E (2023) A marine cryptochrome with an inverse photo-oligomerization mechanism. Nat Commun, 14:6918 (*indicates joint contribution) Link   

2022

Gräf JF, Mikicic I, Ping X, Scalera C, Mayr K, Stelzl LS, Beli P and Wagner SA (2022) Substrate spectrum of PPM1D in the cellular response to DNA double-strand breaks. iScience, 25:104892 Link

Mosler T, Baymaz HI, Gräf JF, Mikicic I, Blattner G, Bartlett E, Ostermaier M, Piccinno R, Yang J, Voigt A, Gatti M, Pellegrino S, Altmeyer M, Luck K, Ahel I, Roukos V and Beli P (2022) PARP1 proximity proteomics reveals interaction partners at stressed replication forks. Nucleic Acids Res, 50:11600-11618 Link

Poehn B, Krishnan S, Zurl M, Coric A, Rokvic D, Häfker NS, Jaenicke E, Arboleda E, Orel L, Raible F, Wolf E and Tessmar-Raible K (2022) A cryptochrome adopts distinct moon- and sunlight states and functions as sun- versus moonlight interpreter in monthly oscillator entrainment. Nat Commun, 13:5220 Link 

Schreier J, Dietz S, Boermel M, Oorschot V, Seistrup AS, de Jesus Domingues AM, Bronkhorst AW, Nguyen DAH, Phillis S, Gleason EJ, L'Hernault SW, Phillips CM, Butter FK and Ketting RF (2022) Membrane-associated cytoplasmic granules carrying the Argonaute protein WAGO-3 enable paternal epigenetic inheritance in Caenorhabditis elegans. Nat Cell Biol, 24:217-229 Link  

Wegmann S, Meister C, Renz C, Yakoub G, Wollscheid HP, Takahashi DT, Mikicic I, Beli P and Ulrich HD (2022) Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass. Mol Cell, 82:1589-1602 Link

2021

Davies C, Ooi CP, Sioutas G, Hall BS, Sidhu H, Butter F, Alsford S, Wickstead B and Rudenko G (2021) TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei. Nucleic Acids Res, 49:3242-3262 Link

Dietz S, Almeida MV, Nischwitz E, Schreier J, Viceconte N, Fradera-Sola A, Renz C, Ceron-Noriega A, Ulrich HD, Kappei D, Ketting RF and Butter F (2021) The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1. Nat Commun, 12:2668 Link

Eisenhuth N, Vellmer T, Rauh ET, Butter F and Janzen CJ (2021) A DOT1B/Ribonuclease H2 protein complex is involved in R-loop processing, genomic integrity, and antigenic variation in Trypanosoma brucei. mBio, 12:e0135221 Link

Lückstädt W, Bub S, Koudelka T, Pavlenko E, Peters F, Somasundaram P, Becker-Pauly C, Lucius R, Zunke F and Arnold P (2021) Cell surface processing of CD109 by meprin β leads to the release of soluble fragments and reduced expression on extracellular vesicles. Front Cell Dev Biol, 9:622390 Link

Maynard D, Viehhauser A, Knieper M, Dreyer A, Manea G, Telman W, Butter F, Chibani K, Scheibe R and Dietz KJ (2021) The in vitro interaction of 12-oxophytodienoic acid and related conjugated carbonyl compounds with thiol antioxidants. Biomolecules, 11:457 Link

Mosler T, Conte F, Longo GMC, Mikicic I, Kreim N, Möckel MM, Petrosino G, Flach J, Barau J, Luke B, Roukos V and Beli P (2021) R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability. Nat Commun, 12:7314 Link

Wagner SA, Szczesniak PP, Voigt A, Gräf JF and Beli P (2021) Proteomic analysis of tyrosine phosphorylation induced by exogenous expression of oncogenic kinase fusions identified in lung adenocarcinoma. Proteomics, 21:e2000283 Link

Worpenberg L, Paolantoni C, Longhi S, Mulorz MM, Lence T, Wessels HH, Dassi E, Aiello G, Sutandy FXR, Scheibe M, Edupuganti RR, Busch A, Möckel MM, Vermeulen M, Butter F, König J, Notarangelo M, Ohler U, Dieterich C, Quattrone A, Soldano A and Roignant JY (2021) Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila. EMBO J, 40:e104975 Link

2020

Casas-Vila N, Sayols S, Pérez-Martínez L, Scheibe M and Butter F (2020) The RNA fold interactome of evolutionary conserved RNA structures in S. cerevisiae. Nat Commun, 11:2789 Link

Dold A, Han H, Liu N, Hildebrandt A, Brüggemann M, Rücklé C, Hänel H, Busch A, Beli P, Zarnack K, König J, Roignant JY and Lasko P (2020) Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation. PLoS Genet, 16:e1008581 Link

Kiweler N, Wünsch D, Wirth M, Mahendrarajah N, Schneider G, Stauber RH, Brenner W, Butter F and Krämer OH (2020) Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes. J Cancer Res Clin Oncol, 146:343-356 Link 

Leismann J, Spagnuolo M, Pradhan M, Wacheul L, Vu MA, Musheev M, Mier P, Andrade-Navarro MA, Graille M, Niehrs C, Lafontaine DL and Roignant JY (2020) The 18S ribosomal RNA m⁶ A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. EMBO Rep, 21:e49443 Link

Pérez-Martínez L, Öztürk M, Butter F and Luke B (2020) Npl3 stabilizes R-loops at telomeres to prevent accelerated replicative senescence. EMBO Rep, 21:e49087 Link

Scherer M, Levin M, Butter F and Scheibe M (2020) Quantitative proteomics to identify nuclear RNA-binding proteins of malat1. Int J Mol Sci, 21:1166 Link 

2019

Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger JB, Busch A, Hänel H, Voigt A, Möckel MM, Ebersberger S, Scholz A, Dold A, Schmid T, Ebersberger I, Roignant JY, Zarnack K, König J and Beli P (2019) The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol, 20:216 Link

Schmidt J, Decker H and Marx MT (2019) Jumping on the edge-first evidence for a 2 × 6-meric hemocyanin in springtails. Biomolecules, 9:396 Link

Schüle KM, Leichsenring M, Andreani T, Vastolo V, Mallick M, Musheev MU, Karaulanov E and Niehrs C (2019) GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells. Genes Dev, 33:782–798 Link

2018

Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA and Beli P (2018) p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. Nat Commun, 9:1017 Link

Heidelberger JB, Voigt A, Borisova ME, Petrosino G, Ruf S, Wagner SA and Beli P (2018) Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function. EMBO Rep, 19:e44754 Link

Knuckles P*, Lence T*, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M and Roignant JY (2018) Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. Genes Dev, 32:415–429 (*indicates joint contribution) Link

Nayak T, Trotter J, and Sakry D (2018) The intracellular cleavage product of the NG2 proteoglycan modulates translation and cell-cycle kinetics via effects on mTORC1/FMRP Signaling. Front Cell Neurosci, 12:231 Link

2017

Chitale S and Richly H (2017) Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation. Oncotarget, 8:30870–30887 Link

2016

Lence T, Akhtar J, Bayer M, Schmid K, Spindler L, Ho CH, Kreim N, Andrade-Navarro MA, Poeck B, Helm M and Roignant JY (2016) m(6)A modulates neuronal functions and sex determination in Drosophila. Nature, 540:242–247 Link

Thakurela S, Garding A, Jung RB, Müller C, Goebbels S, White R, Werner HB and Tiwari VK (2016) The transcriptome of mouse central nervous system myelin. Sci Rep, 6:25828 Link