Papsdorf Lab

2023

Papsdorf K, Miklas JW, Hosseini A, Cabruja M, Morrow CS, Savini M, Yu Y, Silva-García CG, Haseley NR, Murphy LM, Yao P, de Launoit E, Dixon SJ, Snyder MP, Wang MC, Mair WB and Brunet A (2023) Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids. Nat Cell Biol, 25:672-684 Link

Silva-García CG, Láscarez-Lagunas LI, Papsdorf K, Heintz C, Prabhakar A, Morrow CS, Pajuelo Torres L, Sharma A, Liu J, Colaiácovo MP, Brunet A and Mair WB (2023) The CRTC-1 transcriptional domain is required for COMPASS complex-mediated longevity in C. elegans. Nat Aging, 3:1358-1371 Link

2021

Cabruja M, Priotti J, Domizi P, Papsdorf K, Kroetz DL, Brunet A, Contrepois K  and Snyder MP (2021) In-depth triacylglycerol profiling using MS(3) Q-Trap mass spectrometry. Anal Chim Acta, 1184:339023 Link

2019

Papsdorf K and Brunet A (2019) Linking lipid metabolism to chromatin regulation in aging. Trends Cell Biol, 29:97-116 Link

Papsdorf K, Sima S, Schmauder L, Peter S, Renner L, Hoffelner P and Richter K (2019) Head-bent resistant Hsc70 variants show reduced Hsp40 affinity and altered protein folding activity. Sci Rep, 9:11955 Link

2018

Contrepois K, Mahmoudi S, Ubhi BK, Papsdorf K, Hornburg D, Brunet A and Snyder M (2018) Cross-platform comparison of untargeted and targeted lipidomics approaches on aging mouse plasma. Sci Rep, 8:17747 Link

2016

Papsdorf K, Sima S, Richter G and Richter K (2016) Construction and evaluation of yeast expression networks by database-guided predictions. Microb Cell, 3:236-247 Link

2015

Papsdorf K, Kaiser CJ, Drazic A, Grötzinger SW, Haeßner C, Eisenreich W and Richter K (2015) Polyglutamine toxicity in yeast induces metabolic alterations and mitochondrial defects. BMC Genomics, 16:662 Link

2014

Papsdorf K and Richter K (2014) Protein folding, misfolding and quality control: the role of molecular chaperones. Essays Biochem, 56:53-68 Link

Papsdorf K, Sacherl J and Richter K (2014) The balanced regulation of Hsc70 by DNJ-13 and UNC-23 is required for muscle functionality. J Biol Chem, 289:25250-25261 Link

2013

Haslbeck V, Eckl JM, Kaiser CJ, Papsdorf K, Hessling M and Richter K (2013) Chaperone-interacting TPR proteins in Caenorhabditis elegans. J Mol Biol, 425:2922-2939 Link

Kaiser CJ, Grötzinger SW, Eckl JM, Papsdorf K, Jordan S and Richter K (2013) A network of genes connects polyglutamine toxicity to ploidy control in yeast. Nat Commun, 4:1571 Link

2012

Sun L, Edelmann FT, Kaiser CJ, Papsdorf K, Gaiser AM and Richter K (2012) The lid domain of Caenorhabditis elegans Hsc70 influences ATP turnover, cofactor binding and protein folding activity. PLoS One, 7:e33980 Link